Ph. Eur. 2.4.24 & ICH Q3C Residual Solvents Purge Calculator.
Evaluate Headspace GC-MS residual solvent readings in ppm (mg/kg = ug/g) for n-Butane, Isobutane, Propane, Ethanol, Isopropanol, and Class 2 n-Hexane against strict pulmonary inhalation purge targets and Ph. Eur. 2.4.24 / ICH Q3C limits.
Ph. Eur. 2.4.24 & ICH Q3C Residual Solvents (Butane, Propane, Ethanol & n-Hexane) Purge Calculator
Evaluate Headspace GC-MS residual solvent readings in ppm (mg/kg = ug/g) for BHO, live resin, CO2/ethanol winterized extracts, and distillates against strict pulmonary inhalation purge targets and ICH Q3C Class 2/3 limits.
Ph. Eur. 2.4.24 / ICH Q3C Residual Solvents & Stoichiometric Reference Table
| Starting Flower Weight | Raw THCA % | Total Raw THCA (mg) | Max Theoretical THC (0.877x) | Controlled PID + MCT Oil (~83% Net) | Open Kitchen Oven + Butter (~59% Net) | Per Serving (24 Portions) |
|---|---|---|---|---|---|---|
| 3.5 g (Eighth) | 18% THCA | 630 mg | 552.5 mg | 457.5 mg THC | 328.2 mg THC | 19.1 mg (PID) vs 13.7 mg (Oven) |
| 3.5 g (Eighth) | 24% THCA | 840 mg | 736.7 mg | 610.0 mg THC | 437.6 mg THC | 25.4 mg (PID) vs 18.2 mg (Oven) |
| 7.0 g (Quarter) | 20% THCA | 1,400 mg | 1,227.8 mg | 1,016.6 mg THC | 729.3 mg THC | 42.4 mg (PID) vs 30.4 mg (Oven) |
| 7.0 g (Quarter) | 22% THCA | 1,540 mg | 1,350.6 mg | 1,118.3 mg THC | 802.2 mg THC | 46.6 mg (PID) vs 33.4 mg (Oven) |
| 14.0 g (Half Ounce) | 22% THCA | 3,080 mg | 2,701.2 mg | 2,236.6 mg THC | 1,604.5 mg THC | 93.2 mg (PID) vs 66.9 mg (Oven) |
| 28.0 g (One Ounce) | 25% THCA | 7,000 mg | 6,139.0 mg | 5,083.1 mg THC | 3,646.6 mg THC | 211.8 mg (PID) vs 151.9 mg (Oven) |
Frequently Asked Engineering Questions
Under Ph. Eur. 2.4.24 and ICH Q3C, Class 2 solvents (such as n-Hexane, limit <= 290 ppm, and Methanol, limit <= 3,000 ppm) exhibit non-genotoxic neurotoxic or systemic toxicity and must be strictly limited, whereas Class 3 solvents (such as Ethanol, Isopropanol, Acetone, and pure n-Butane/Propane, oral limit <= 5,000 ppm) have lower systemic toxicity, though inhaled cannabis extracts target <= 800 ppm for hydrocarbons to prevent airway irritation.
Because ice-water bubble hash and mechanical heat-press rosin use only chilled water, ice, and physical pressure (zero hydrocarbons, alcohols, or supercritical gases), they contain 0 ppm of petrochemical or alcohol residual solvents by design.
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